2010 – 2019 © GeneXplain GmbH

GeneXplain provides a comprehensive platform for Bioinformatics, System Biological, and Cheminformatics. We are mainly in charge of various researches of life science in Personalized Medicine and Pharmacogenomics.

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2010 – 2019 © GeneXplain GmbH

GeneXplain is a new company, with the mission to provide a comprehensive platform for bioinformatic, cheminformatic and systems biological tools.  We intend to make our expertise available to academic and commercial partners in collaborative research projects. Numerous researchers still use geneXplain solutions in various fields.

2010 – 2019 © GeneXplain GmbH

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2010 – 2019 © GeneXplain GmbH

2010 – 2019 © GeneXplain GmbH

2010 – 2019 © GeneXplain GmbH

2010 – 2019 © GeneXplain GmbH

The new relase 2019.3 of the databases is available

Author
admin
Date
2019-10-15 16:34
Views
207

In TRANSFAC® 2019.3 you will find the following new features:

- Increase in Drosophila melanogaster transcription factor interactions: over 2,500 protein-protein interactions from the transcription factor network in fruit flies were added.

- miRNA target site import from miRTarBase: over 3,600 experimentally verified miRNA target sites mostly for human and mouse were added from miRTarBase 7.0. Also, 337 existing sites in TRANSFAC® were updated with further experimental evidence from miRTarBase.

- Matrix, Factor, Gene and Site flat files are now also available in JSON (JavaScript Object Notation) format for TRANSFAC® download customers. JSON is supported by a rich infrastructure of tools in all modern languages and has become the de facto standard for data interchange.

- The result of concatenating search for identification of transcription factors which bind and regulate a set of genes based on experimentally verified data (running a second "binding factors for gene" search by using the result of a gene search as input) now includes information about the regulatory effect type which the factor has on the gene, if this is known.

- Update of genomic information for genes, promoters, and ChIP fragments for human, mouse, rat, pig, macaque, Drosophila, and Arabidopsis to Ensembl release 96.

You can view the full list of TRANSFAC® 2019.3 new features and database statistics for more details.

In TRANSPATH® 2019.3 you will find the following new features:

- Over 7,500 new binding reactions between proteins in human, mouse, rat or fruit fly have been added.

- New phosphorylation targets have been included by integrating 526 reactions catalyzed by the human serine/threonine kinase PRKD3.

You can view the full list of TRANSPATH® 2019.3 new features and database statistics for more details.

In HumanPSD™ 2019.3 you will find the following new features:

- Locus report links to Reactome pathways: many locus reports now contain a table with Reactome pathways the gene/protein is involved in. Over 100,000 hyperlinks to Reactome pathway reports as well as to the Reactome pathway browser have been added.

- More Clinical Trial and Biomarker data: the number of CT-Disease-Drug assignments was increased to 412,475 and the number of disease annotations to 329,469.

You can view the full list of HumanPSD™ 2019.3 new features and database statistics for more details.

The DBs releases 2019.3 integrated in the geneXplain® platform
The releases 2019.3 of TRANSFAC®, TRANSPATH® and HumanPSD™ databases are now available for your analysis in the geneXplain® platform.

If you are not yet a geneXplain® platform user, you are welcome to register for your free account here.
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The new relase 2019.3 of the databases is available
admin | 2019.10.15 | Votes 0 | Views 207
admin 2019.10.15 0 207