2010 – 2019 © GeneXplain GmbH

2010 – 2019 © GeneXplain GmbH

Based on the BioUML technology developed by the Institute of Systems Biology, Bioinformatics is a platform for integrating individual modules called “toolboxes” with regard to System Biology and using well-defined functions. (Transcriptomics, Proteomics, Epigenomics, and Metabolomics) for the entire pipeline.

Click on the icon on the left to see an introduction to geneXplain platform

2010 – 2019 © GeneXplain GmbH

Main Features

  • Collect, store, analyze and export experimental data
  • Microarray, ChIP-seq, Protemoics, GWAS, NGS and other data analysis
  • Extensive Regulatory Genome Regions Analysis Using TRANSFAC Database
  • Mapping to Ontologies or Gene Set Enrichment Analysis (GSEA)
  • Network Clustering, Master Regulator Molecules, Potential Biomarker, Drug Target Analysis using TRANSPATH Database
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Up Stream Analysis
  • About 100 completed Workflow (Specific Pipelines)
  • Create your own workflow using graphical programming
  • You can add your own JavaScript or R Script
  • A useful platform that can be used to extend RNA-seq analysis data to target drug or network analysis

2010 – 2019 © GeneXplain GmbH

Workflow management

The upper image shows a small workflow for Gene Set Enrichment Analysis (GSEA) using four ontologies: Gene Ontology (GO) Biological Process, GO Cellular Compartment, GO Molecular Function and Reactome’s functional assignments (see right). The light blue box is the analysis function (program module, “Brick”). The green box represents the input file, especially the user-defined input. A yellow box indicates an automatic forwarding or output file. Workflows can be set up intuitively because they can be graphically linked by dragging the component.

2010 – 2019 © GeneXplain GmbH